TY - CHAP AU - Juliana de Mattos Coelho-Aguiar AU - Carla Pires Veríssimo AU - Deiziane Viana da Silva Costa AU - Beatriz Bastos de Moraes Thomasi AU - Ana Carina Bon Frauches AU - Fabiana Pereira Ribeiro AU - Ana Lucia Tavares Gomes AU - Gerly Anne de Castro Brito AU - Vivaldo Moura-Neto ED - Tania Spohr Y1 - 2019-12-13 PY - 2019 T1 - The Enteric Glial Network Acts in the Maintenance of Intestinal Homeostasis and in Intestinal Disorders N2 - The book will highlight the role played by glial cells in the central and peripheral nervous systems in both healthy and unhealthy individuals. Among all processes involved, we will discuss the importance of the enteric nervous system in the control of gut homeostasis, in the interaction with the immune system, and its participation in pathological conditions such as metabolic syndrome. We will also look at the relevance of astrocytes during synaptic transmission and the regulation of plasticity by releasing gliotransmitters. Ultimately, we will highlight the influence of astrocytes during the development of a number of neurodegenerative diseases, such as multiple sclerosis and Alzheimer’s disease, focusing on how the serum levels of the astrocytic protein S100B can be used as a biomarker for clinical decisions. BT - Glia in Health and Disease SP - Ch. 3 UR - https://doi.org/10.5772/intechopen.89170 DO - 10.5772/intechopen.89170 SN - 978-1-78985-254-7 PB - IntechOpen CY - Rijeka Y2 - 2024-04-25 ER -