TY  - CHAP
AU  - Polina Povarnina
AU  - Yulia N. Firsova
AU  - Anna V. Tallerova
AU  - Аrmen G. Mezhlumyan
AU  - Sergey V. Kruglov
AU  - Tatiana A. Antipova
AU  - Tatiana A. Gudasheva
AU  - Sergey B. Seredenin
ED  - Olivier Berend
Y1  - 2019-10-23
PY  - 2019
T1  - The BDNF Loop 4 Dipeptide Mimetic Bis(<em>N</em>-monosuccinyl-L-seryl-L-lysine)hexamethylenediamide Is Active in a Depression Model in Mice after Acute Oral Administration
N2  - Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been around since the 1950s, and although current medications are much more effective than early ones, there is still much room for improvement. "Real" antidepressants, defined as those that "repair" or "improve" the depression-causing mechanism in the brains of depressed patients, have yet to be identified. This book presents current research on depression and antidepressants, including use of antidepressants in alcohol use disorders and pregnancy, treatment-resistant depression, and development of potential new medications.
BT  - Antidepressants
SP  - Ch. 6
UR  - https://doi.org/10.5772/intechopen.88244
DO  - 10.5772/intechopen.88244
SN  - 978-1-78985-277-6
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-19
ER  -