TY - CHAP AU - Roxana Adriana Stoica AU - Diana Simona Ștefan AU - Manfredi Rizzo AU - Andra Iulia Suceveanu AU - Adrian Paul Suceveanu AU - Cristian Serafinceanu AU - Anca Pantea-Stoian ED - Anca Mihaela Pantea Stoian ED - Manfredi Rizzo Y1 - 2019-08-28 PY - 2019 T1 - Metformin Indications, Dosage, Adverse Reactions, and Contraindications N2 - The book “Metformin” aims to bring to light new concepts and trends related to the many metformin therapeutic features. After a history of over 60 years, with moments of decline and spectacular returns, metformin can now be regarded as a universal panacea, the valences of its therapeutics being increasingly appreciated, both in the background treatment of diabetes and pre-diabetes, but also in reproductive pathology, cancer, cardiovascular disease, and antiageing. In this respect, the mechanisms of action and the pharmacodynamics of metformin seem to be incompletely known, a number of current studies have revealed new action valences. BT - Metformin SP - Ch. 1 UR - https://doi.org/10.5772/intechopen.88675 DO - 10.5772/intechopen.88675 SN - 978-1-83880-428-2 PB - IntechOpen CY - Rijeka Y2 - 2024-04-19 ER -