TY  - CHAP
AU  - Osman Ugur Sezerman
AU  - Ege Ulgen
AU  - Nogayhan Seymen
AU  - Ilknur Melis Durasi
ED  - Ali Samadikuchaksaraei
ED  - Morteza Seifi
Y1  - 2019-06-14
PY  - 2019
T1  - Bioinformatics Workflows for Genomic Variant Discovery, Interpretation and Prioritization
N2  - Genomic variations and phenotypic diversity are closely linked and form the underlying mechanism for development of many human diseases. This book addresses the methods of detection, analysis, and interpretation of genomic variations in clinically relevant scenarios. If your research or clinical practice involves handling of genomic sequencing data, this book is for you. Topics covered include: methods for identifying genetic diversity, the workflow for analyzing whole exome and whole genome sequencing data, local ancestry deconvolution models, the value of molecular patterns and pattern biomarkers in cancer diagnosis and prognosis, and genotyping and profiling resistance-associated variants of hepatitis C. If your research or clinical practice involves handling of genomic sequencing data, this book is for you.
BT  - Bioinformatics Tools for Detection and Clinical Interpretation of Genomic Variations
SP  - Ch. 2
UR  - https://doi.org/10.5772/intechopen.85524
DO  - 10.5772/intechopen.85524
SN  - 978-1-78923-800-6
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-19
ER  -