TY - CHAP AU - Jose Ordi-Ros AU - Cristina Sole Marce AU - Josefina Cortes-Hernandez ED - Sophia Lionaki Y1 - 2019-02-08 PY - 2019 T1 - Lupus Pregnancy: Risk Factors and Management N2 - Systemic lupus erythematosus, the prototype of an autoimmune disorder, may affect several organs and may run a chronic course between relapse and remission. This book covers important aspects of the disease, including epidemiology, pathophysiology, and neuropsychiatric manifestations, including basic science and clinical features and management. In affected patients, the fundamental problem of fertility is reassessed including the risk of the disease, the possibility of fetal loss, the safety of drugs during pregnancy, and the current diagnostic and suggested therapeutic strategies of reproductive medicine. Finally, the issue of pathogenesis is revisited with a thorough description of animal models in relation to physiology and potential novel therapies. BT - Lupus SP - Ch. 5 UR - https://doi.org/10.5772/intechopen.83652 DO - 10.5772/intechopen.83652 SN - 978-1-83880-170-0 PB - IntechOpen CY - Rijeka Y2 - 2024-04-26 ER -