TY  - CHAP
AU  - Apiwat Mutirangura
ED  - Rosaria Meccariello
Y1  - 2018-12-31
PY  - 2018
T1  - A Hypothesis to Explain How the DNA of Elderly People Is Prone to Damage: Genome-Wide Hypomethylation Drives Genomic Instability in the Elderly by Reducing Youth-Associated Gnome-Stabilizing DNA Gaps
N2  - Epigenetic changes are heritable and reversible modifications that significantly affect gene expression without any change in DNA sequence. The epigenetic signature is remodelled during the lifespan as a direct consequence of both environment and lifestyle. Therefore, health or disease status strongly depends on epigenetic marks. This book summarizes the current knowledge in the field and includes chapters on  epigenetics in plants and epigenetics in health and disease. It is written for a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding of epigenetics.
BT  - Epigenetics
SP  - Ch. 5
UR  - https://doi.org/10.5772/intechopen.83372
DO  - 10.5772/intechopen.83372
SN  - 978-1-78984-088-9
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-24
ER  -