TY - CHAP AU - Raymond W. Nims AU - Amanda Capes-Davis AU - Christopher Korch and Yvonne A. Reid ED - Radwa Ali Mehanna Y1 - 2018-11-05 PY - 2018 T1 - Authenticating Hybrid Cell Lines N2 - Cell culture is one of the major tools used in cellular and molecular biology, delivering an excellent model for studying the normal physiology and biochemistry of cells. This book covers some advanced aspects in cell culture methodologies. The book has four sections discussing different types of cell culture models, including 3D cell culture techniques, their advantages, and limitations in comparison to traditional 2D culturing; cell viability, autophagy, in vitro toxicity tests and live cell imaging; stem cell culture for cell-based therapeutics; and specific applications and methodologies for hybrid cell lines and cancer models. This book provides a comprehensive overview of some of the advanced cell culture methodologies and applications. It serves as a valuable source for scientists, researchers, clinicians and students. BT - Cell Culture SP - Ch. 8 UR - https://doi.org/10.5772/intechopen.80669 DO - 10.5772/intechopen.80669 SN - 978-1-78984-867-0 PB - IntechOpen CY - Rijeka Y2 - 2024-04-18 ER -