TY  - CHAP
AU  - Katherine Ognenovska
AU  - Vera Klemm
AU  - Scott Ledger
AU  - Stuart Turville
AU  - 
Geoff Symonds
AU  - Anthony D. Kelleher
AU  - Chantelle L. Ahlenstiel
ED  - Houria Bachtarzi
Y1  - 2018-11-05
PY  - 2018
T1  - Mechanisms for Controlling HIV-1 Infection: A Gene Therapy Approach
N2  - Ongoing advances in pharmaceutical biotechnology have paved the way to ground-breaking new biological therapeutic modalities, offering the possibility of a durable curative approach for a number of life-threatening diseases, for which the medical need is as yet unmet. Over the past decades, gene therapy has seen a massive transformation from a proof-of-concept approach to a clinical reality culminating in the regulatory approval of state-of-the-art products in the European Union and in the United States. This book captures some of the scientific progresses notably in gene transfer technologies and translational development of in vivo and ex vivo gene therapy interventions in the treatment of a broad range of complex and debilitating non-inherited and inherited disorders such as: human immunodeficiency virus 1 (HIV-1) infection, cancer, cystic fibrosis, hereditary retinopathies, haemophilia B, cardiac diseases, and chronic liver fibrosis.
BT  - In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders
SP  - Ch. 3
UR  - https://doi.org/10.5772/intechopen.79669
DO  - 10.5772/intechopen.79669
SN  - 978-1-78985-718-4
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-18
ER  -