TY - CHAP AU - Ileana Cornelia Farcasanu AU - Claudia Valentina Popa AU - Lavinia Liliana Ruta ED - John N. Buchholz ED - Erik J. Behringer Y1 - 2018-10-24 PY - 2018 T1 - Calcium and Cell Response to Heavy Metals: Can Yeast Provide an Answer? N2 - Since the development of microelectronic clamping methodology and fluorescent indicators for direct measurement of dynamic intracellular calcium transients, our understanding of biological signal transduction has progressed dramatically since the 1980s. Calcium is a universal signal in biology that modulates gene expression, transmitter and hormone release, muscular movement, and even "programmed" cell death. This book represents a compilation of chapters from a diverse set of expert biologists throughout the world who have conducted research in the general area of calcium signaling in organisms ranging from bacteria to humans. In accord with priorities of resolving human disease, the reader will also benefit from learning calcium's role in cellular signaling pathology relating to acute or chronic conditions such as vomiting, sepsis, obesity, hypertension, and cancer. BT - Calcium and Signal Transduction SP - Ch. 2 UR - https://doi.org/10.5772/intechopen.78941 DO - 10.5772/intechopen.78941 SN - 978-1-78984-250-0 PB - IntechOpen CY - Rijeka Y2 - 2024-03-29 ER -