TY - CHAP AU - Christy Xavier AU - Xiaobin Liu AU - Yang Liu AU - Hongli Wu ED - Pinar Erkekoglu ED - Belma Kocer-Gumusel Y1 - 2018-11-05 PY - 2018 T1 - The Important Functions of GSH-Dependent Enzyme Glutaredoxin 2 (Grx2) N2 - Reduced glutathione (GSH) is the most important thiol in living organisms. It is the key component of antioxidant system and serves as a free radical scavenger. There is a cycle of GSH in biological systems and this cycle provides higher intracellular levels of GSH. GSH depletion and apparent oxidative stress may cause toxicity and can affect the general well-being of the organism. GSH was shown to be preventive against aging, cancer, heart disease, infections and dementia. This book is mainly focused on GSH in health and disease. The readers will gain qualified scientific knowledge on the diverse functions of GSH, the importance of GSH status against oxidative stress and the interaction between GSH and nervous system-related infections from this book. BT - Glutathione in Health and Disease SP - Ch. 3 UR - https://doi.org/10.5772/intechopen.78653 DO - 10.5772/intechopen.78653 SN - 978-1-78984-276-0 PB - IntechOpen CY - Rijeka Y2 - 2024-05-10 ER -