TY - CHAP AU - Yafei Chen ED - J. Eric McDuffie Y1 - 2018-11-05 PY - 2018 T1 - Induced Pluripotent Stem Cell-Derived Human Glutamatergic Neurons as a Platform for Mechanistic Assessment of Inducible Excitotoxicity in Drug Discovery N2 - Toxicologists seek to better understand the myriad of mechanisms responsible for neurotoxins. Because the incidence of neurobehavioral hazards and risks of exogenous compounds (e.g., natural toxins, synthetic molecules, and therapeutic agents) remain a subject matter of interest, predictive tools have evolved, including but not limited to novel translational in vitro models, biomarkers, newer epidemiological research tools, and well-accepted best practices for diagnosing neurotoxins in clinical practice. Taken together, the foreseen need to highlight some of the more appreciated and/or emerging tactical approaches in neurotoxicology results in a "one-stop reference" book, Neurotoxins. BT - Neurotoxins SP - Ch. 2 UR - https://doi.org/10.5772/intechopen.77043 DO - 10.5772/intechopen.77043 SN - 978-1-78923-169-4 PB - IntechOpen CY - Rijeka Y2 - 2024-04-24 ER -