TY  - CHAP
AU  - Philip Aston
AU  - Katie Cranfield
AU  - Haley O’Farrell
AU  - Alex Cassenote
AU  - Cassia
J. Mendes-Correa
AU  - Aluisio Segurado
AU  - Phuong Hoang
AU  - George
Lankford
AU  - Hien Tran
ED  - Imran Shahid
Y1  - 2018-04-10
PY  - 2018
T1  - Hepatitis C Viral Dynamics Using a Combination Therapy of Interferon, Ribavirin, and Telaprevir: Mathematical Modeling and Model Validation
N2  - The propagation of hepatitis C from acute to chronic infection and afterward to end-stage liver diseases (hepatic fibrosis, cirrhosis, and hepatocellular carcinoma) involves a highly orchestrated series of molecular and cellular events, including a plethora of genes and cell signaling cascades. The treatment paradigms was revolutionized after the development and approval of all oral interferon-free direct-acting antivirals achieving higher sustained virologic response rates in treated individuals. This book pragmatically overviews the intricate interplay between viral and host factors during hepatitis C virus infection progression, as well as other hepatitis C-associated clinical implications. Hepatitis C - From Infection to Cure also provides up-to-date information about hepatitis C cures for clinicians, physicians, and healthcare providers with an ample understanding of the current treatment horizon, as well as other investigational and emerging treatment strategies. The authors with their valuable scientific contributions belong to many eminent institutes around the world and are much experienced in hepatitis C virology, pathology, and therapeutics.
BT  - Hepatitis C
SP  - Ch. 10
UR  - https://doi.org/10.5772/intechopen.75761
DO  - 10.5772/intechopen.75761
SN  - 978-1-78984-208-1
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-25
ER  -