TY  - CHAP
AU  - Jan Beute
AU  - Vincent Manganiello
AU  - Alex KleinJan
ED  - Kuan-Hsiang Gary Huang
ED  - Chen Hsuan Sherry Tsai
Y1  - 2018-02-28
PY  - 2018
T1  - Phosphodiesterase 3 and 4 Inhibition: Facing a Bright Future in Asthma Control
N2  - Asthma is a severe and growing threat affecting both children and adults in both developing and developed world, currently affecting approximately 8% of US population. It is becoming increasingly recognized as a syndrome constituted by airway obstruction, airway hyperresponsiveness, and airway inflammation with different causes, associated risk factors, and underlying pathophysiology. The advances in basic and clinical research of asthma have accelerated over the past 20 years with increasing diagnostic tools, especially biomarkers, that led to specific characterization of individual patient's asthma pathophysiology, or disease "phenotype" and "endotype," which allowed precision medicine therapies, including new asthma biologics. This book aims to update the paradigm shifts in precision medicine of asthma diagnosis and management, driven by underlying phenotypes or endotypes.
BT  - Asthma Diagnosis and Management
SP  - Ch. 6
UR  - https://doi.org/10.5772/intechopen.74309
DO  - 10.5772/intechopen.74309
SN  - 978-1-78923-323-0
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-18
ER  -