TY - CHAP AU - Jie Liu AU - Huan Li AU - Shangfu Xu AU - Yunyan Xu AU - Chang Liu ED - Mohamed Ahmed El-Esawi Y1 - 2018-02-16 PY - 2018 T1 - Circadian Clock Gene Expression and Drug/Toxicant Interactions as Novel Targets of Chronopharmacology and Chronotoxicology N2 - Circadian clocks are endogenous and temperature-compensating timekeepers that provide temporal organization of biological processes in living organisms. Circadian rhythms allow living organisms to adapt to the daily light cycles associated with Earth's rotation and to anticipate and prepare for precise and regular environmental changes. This book discusses the fundamental advances of how the circadian clock regulates critical biological functions as well as the cellular and molecular mechanisms controlling circadian rhythm in living organisms. It also provides new insights into and sheds new light on the current research trends and future research directions related to circadian rhythm. This book provokes interest in many readers, researchers and scientists, who can find this information useful for the advancement of their research works towards a better understanding of circadian rhythm regulatory mechanisms. BT - Circadian Rhythm SP - Ch. 3 UR - https://doi.org/10.5772/intechopen.74597 DO - 10.5772/intechopen.74597 SN - 978-1-78923-339-1 PB - IntechOpen CY - Rijeka Y2 - 2024-04-18 ER -