TY - CHAP AU - Margarete Dulce Bagatini AU - Jeandre Augusto dos Santos Jaques AU - Carla Santos de Oliveira AU - Graciele Almeida de Oliveira AU - Micheli Mainardi Pillat AU - Aline Mânica AU - Cintia dos Santos Moser AU - Lucas Derbocio dos Santos AU - Henning Ulrich ED - Pinar Atukeren Y1 - 2018-04-06 PY - 2018 T1 - Oxidative Stress: Noxious but Also Vital N2 - Oxidative stress plays a crucial role in the pathophysiology of various diseases when there is a disruption of the intracellular redox balance and the homeostatic balance between cellular oxidants and antioxidants. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) react with molecular targets including proteins, lipids, and nucleic acids contributing to mitochondrial injury and cellular dysfunction. This book intends to provide the readers with an extensive overview of the novel approaches and prospects based on oxidative and nitrosative stress in the pathophysiology of various diseases and in the current treatment strategies with antioxidants. BT - Novel Prospects in Oxidative and Nitrosative Stress SP - Ch. 1 UR - https://doi.org/10.5772/intechopen.73394 DO - 10.5772/intechopen.73394 SN - 978-1-78923-087-1 PB - IntechOpen CY - Rijeka Y2 - 2024-04-18 ER -