TY - CHAP AU - Riikka Lampinen AU - Irina Belaya AU - Isabella Boccuni AU - Tarja Malm and Katja M. Kanninen ED - Maria Teresa Gentile ED - Luca Colucci D’Amato Y1 - 2017-12-20 PY - 2017 T1 - Mitochondrial Function in Alzheimer’s Disease: Focus on Astrocytes N2 - A team of authors from prestigious academic schools contributed to draw up a project that would give a detailed account of astrocyte's morphology and physiology, examining thoroughly all the astrocyte's types; giving an accurate description of their morphology, location, function in the brain; and illustrating their physiology and pathology in terms of dealing with neurons through "gliotransmitters," ionic channels, and membrane receptors expression. This book gives an overview of the crucial role of astrocytes in the physiology of the CNS and in the pathogenesis of several CNS disorders suggesting that the shift from a neurocentric view to one that incorporates astrocytes in disease models for drug discovery is a critical step in renewing drug development strategies to treat neurodegenerative diseases. BT - Astrocyte SP - Ch. 7 UR - https://doi.org/10.5772/intechopen.71825 DO - 10.5772/intechopen.71825 SN - 978-953-51-3886-0 PB - IntechOpen CY - Rijeka Y2 - 2024-04-27 ER -