TY - CHAP AU - Kingsley Asare Kwadwo Pereko AU - Jacob Setorglo AU - Matilda Steiner- Asiedu AU - Joyce Bayebanona Maaweh Tiweh ED - Rodrigo Valenzuela Y1 - 2018-03-21 PY - 2018 T1 - Nutrition and Lifestyle Modifications in the Prevention and Treatment of Non-Alcoholic Fatty Liver Disease N2 - Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances such as insulin resistance, inflammation, and oxidative stress, considered as the hepatic manifestation of metabolic syndrome. There is no effective drug therapy for this disease; therefore, lifestyle interventions remain as the first-line treatment. Nevertheless, the adherence rates to this type of treatment are very low, so great efforts are focused at finding novel therapeutic agents for the prevention of hepatic steatosis and its progression. This book presents a systematic and comprehensive revision about NAFLD, highlighting its epidemiological and molecular aspects, as well as its prevention and treatment. BT - Non-Alcoholic Fatty Liver Disease SP - Ch. 7 UR - https://doi.org/10.5772/intechopen.71368 DO - 10.5772/intechopen.71368 SN - 978-953-51-3924-9 PB - IntechOpen CY - Rijeka Y2 - 2024-04-24 ER -