TY - CHAP AU - Claudia Castruita-De la Rosa AU - Idalia Garza-Veloz AU - Edith Cardenas- Vargas AU - Rodrigo Castañeda-Miranda AU - Luis O. Solis-Sanchez AU - Jose M. Ortiz-Rodriguez AU - Hector R. Vega-Carrillo AU - Maria R. Martinez-Blanco AU - Virginia Flores-Morales AU - Gloria P. Hernandez-Delgadillo AU - Jose I. Badillo-Almaráz AU - Margarita L. Martinez-Fierro ED - Francesco Travascio Y1 - 2017-12-20 PY - 2017 T1 - Biological Activity and Implications of the Metalloproteinases in Diabetic Foot Ulcers N2 - Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body. BT - The Role of Matrix Metalloproteinase in Human Body Pathologies SP - Ch. 8 UR - https://doi.org/10.5772/intechopen.71725 DO - 10.5772/intechopen.71725 SN - 978-953-51-3718-4 PB - IntechOpen CY - Rijeka Y2 - 2024-04-19 ER -