TY  - CHAP
AU  - Min Yao
AU  - Wenjie Zheng
AU  - Li Wang
AU  - Miao Fang
AU  - Dengfu Yao and
Zhizheng Dong
ED  - Costin Teodor Streba
ED  - Cristin Constantin Vere
ED  - Ion Rogoveanu
Y1  - 2017-12-21
PY  - 2017
T1  - Oncogenic Secretory Clusterin: A Promising Therapeutic Target for Hepatocellular Carcinoma
N2  - Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated, imaging methods being considered as sufficient diagnostic tools. Molecular characterization remains desirable, since chemotherapeutic agents still have limited applicability. In light of recent diagnostic advancements and novel therapeutic solutions, it is our belief that a comprehensive update on recent paradigm shifts and interesting upcoming developments is highly needed.
BT  - Hepatocellular Carcinoma
SP  - Ch. 6
UR  - https://doi.org/10.5772/intechopen.71007
DO  - 10.5772/intechopen.71007
SN  - 978-1-78984-274-6
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-25
ER  -