TY - CHAP AU - Dania Movia AU - Adriele Prina-Mello ED - Andreia C. Gomes ED - Marisa P. Sarria Y1 - 2017-12-20 PY - 2017 T1 - Nanotoxicity in Cancer Research: Technical Protocols and Considerations for the Use of 3D Tumour Spheroids N2 - As nanomaterials become increasingly present in our daily lives, pertinent questions regarding their safety arise. Nanomaterial risk assessment, as in other areas, directs much of the effort worldwide in defining guidelines that may be translated into national or international directives. Nanomaterials encompass different entities, from nanoparticles to nanostructured materials, with specific effects over cells, tissues, organisms and ecosystems depending on their biophysical characteristics. Such interactions will directly affect the impact of novel nanotechnologies. This book aims to provide the reader with a comprehensive overview of the current state of the art in nanotoxicology, featuring the most important developments and critical issues regarding the use of and exposure to nanoparticles. BT - Unraveling the Safety Profile of Nanoscale Particles and Materials SP - Ch. 5 UR - https://doi.org/10.5772/intechopen.69447 DO - 10.5772/intechopen.69447 SN - 978-953-51-3940-9 PB - IntechOpen CY - Rijeka Y2 - 2024-03-29 ER -