TY - CHAP AU - Jacqueline A. Leite AU - Ana Maria M. Orellana AU - Paula F. Kinoshita AU - Natália P. de Mello AU - Cristoforo Scavone AU - Elisa M. Kawamoto ED - Gonzalo Emiliano Aranda Abreu Y1 - 2017-08-23 PY - 2017 T1 - Neuroinflammation and Neurotransmission Mechanisms Involved in Neuropsychiatric Disorders N2 - "Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system. BT - Mechanisms of Neuroinflammation SP - Ch. 2 UR - https://doi.org/10.5772/intechopen.69343 DO - 10.5772/intechopen.69343 SN - 978-953-51-3452-7 PB - IntechOpen CY - Rijeka Y2 - 2024-05-11 ER -