TY - CHAP AU - Pran Kishore Deb AU - Raghu Prasad Mailabaram AU - Bilal Al-Jaidi and Mohamed Jamal Saadh ED - Ali Gamal Ahmed Al-kaf Y1 - 2017-08-23 PY - 2017 T1 - Molecular Basis of Binding Interactions of NSAIDs and Computer-Aided Drug Design Approaches in the Pursuit of the Development of Cyclooxygenase-2 (COX-2) Selective Inhibitors N2 - This book intends to provide the reader with a comprehensive overview about the state of the art regarding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in physical and rehabilitation medicine and the study of the pharmacodynamics of existing and newly introduced NSAIDs in the management of pain and inflammation. It will also elaborate and refine already known knowledge on the mechanism(s) of nonsteroidal anti-inflammatory agents. This book may provide additional knowledge about the design and development of new drug delivery systems loaded with NSAIDs potentially useful in the treatment of chronic inflammatory-based diseases following circadian cycle, uses of NSAIDs as a source of medicinal plants, and the adverse effects and drug interactions of the nonsteroidal anti-inflammatory drugs. BT - Nonsteroidal Anti-Inflammatory Drugs SP - Ch. 6 UR - https://doi.org/10.5772/intechopen.68318 DO - 10.5772/intechopen.68318 SN - 978-953-51-3444-2 PB - IntechOpen CY - Rijeka Y2 - 2024-05-10 ER -