TY - CHAP AU - Guy Joseph Lemamy AU - Bénédicte Ndeboko AU - Serge Thierry Omouessi and Justine Mouecoucou ED - Maria del Carmen Cardenas- Aguayo Y1 - 2016-10-12 PY - 2016 T1 - Mannose-6-Phosphate/Insulin-Like Growth Factor 2 Receptor (M6P/IGF2-R) in Growth and Disease: A Review N2 - Restricted growth conditions are a group of genetic disorders with primary effect on growth (short stature); it is very heterogeneous and comprises two important categories: skeletal dysplasia and different genetic syndromes with primary effect on growth. It could also be caused by a medical condition. The book contains chapters regarding different aspects of the study of restricted growth that are divided into three broad sections. Section I: Defining Restricted Growth, Section II: Genetics and Diagnosis of Restricted Growth, and Section III: Signaling Pathways and Molecular Mechanisms of Restricted Growth. The book presents comprehensive reviews of each topic written by experts in the field. It will be the most valuable tool for physicians and life science researchers and students. We hope that the book will motivate discussion and research in this important health problem, setting the path for better therapeutic approaches. BT - Restricted Growth SP - Ch. 6 UR - https://doi.org/10.5772/64810 DO - 10.5772/64810 SN - 978-953-51-2695-9 PB - IntechOpen CY - Rijeka Y2 - 2024-03-28 ER -