TY  - CHAP
AU  - Claudia Ntsapi
AU  - Chrisna Swart
AU  - Dumisile Lumkwana
AU  - Ben Loos
ED  - Nikolai V. Gorbunov
ED  - Marion Schneider
Y1  - 2016-11-10
PY  - 2016
T1  - Autophagic Flux Failure in Neurodegeneration: Identifying the Defect and Compensating Flux Offset
N2  - Autophagy in Current Trends in Cellular Physiology and Pathology is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period. Particular attention is paid to autophagy-mediated barrier processes of selective sequestration and recycling of impaired organelles and degradation of invading microorganisms, that is, the processes sustaining intrinsic resistance to stress, tissue degeneration, toxic exposures, and infections. The presented topics encompass personal experience and visions of the chapter contributors and the editors; the book chapters include a broad analysis of literature on biology of autophagy.
BT  - Autophagy in Current Trends in Cellular Physiology and Pathology
SP  - Ch. 9
UR  - https://doi.org/10.5772/64197
DO  - 10.5772/64197
SN  - 978-953-51-2727-7
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-26
ER  -