TY - CHAP AU - Lei Yu AU - Jennifer Batara AU - Biao Lu ED - Michael S.D. Kormann Y1 - 2016-05-18 PY - 2016 T1 - Application of Genome Editing Technology to MicroRNA Research in Mammalians N2 - Site-specific endonucleases create double-strand breaks within the genome and can be targeted to literally any genetic mutation. Together with a repair template, a correction of the defective locus becomes possible. This book offers insight into the modern tools of genome editing, their hurdles and their huge potential. A new era of in vivo genetic engineering has begun. BT - Modern Tools for Genetic Engineering SP - Ch. 7 UR - https://doi.org/10.5772/64330 DO - 10.5772/64330 SN - 978-953-51-2234-0 PB - IntechOpen CY - Rijeka Y2 - 2024-04-18 ER -