TY - CHAP AU - Katy S. Orr AU - Kienan I. Savage ED - Clark C. Chen Y1 - 2015-11-18 PY - 2015 T1 - The BRCA1 and BRCA2 Breast and Ovarian Cancer Susceptibility Genes — Implications for DNA Damage Response, DNA Repair and Cancer Therapy N2 - This book edition is intended to provide a concise summary for select topics in DNA repair, a field that is ever-expanding in complexity and biologic significance. The topics reviewed ranged from fundamental mechanisms of DNA repair to the interface between DNA repair and a spectrum on cellular process to the clinical relevance of DNA repair in oncologic paradigms. The information in this text should provide a foundation from which one can explore the various topics in depth. The book serve as a supplementary text in seminar courses with focus on DNA repair as well as a general reference for scholars with an interest in DNA repair. BT - Advances in DNA Repair SP - Ch. 7 UR - https://doi.org/10.5772/59996 DO - 10.5772/59996 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-25 ER -