TY  - CHAP
AU  - Zhengzhi Feng
AU  - Xiaoxia Wang
AU  - Keyu Liu
AU  - Xiao Liu
AU  - Lifei Wang
AU  - Xiao Chen
AU  - Qin Dai
ED  - Yong-Ku Kim
Y1  - 2015-06-11
PY  - 2015
T1  - The Neural Mechanism of Negative Cognitive Bias in Major Depression — Theoretical and Empirical Issues
N2  - Major depressive disorder (MDD) is a complex and heterogeneous disorder, phenotypically and biologically. MDD may be caused by complex interaction between genes and environment in susceptible individuals. Thus, a combination of certain genetic polymorphism, environmental stress, and personal susceptibility ultimately may induce MDD. Gene-environment interactions in the pathophysiology of MDD lead to advancement in personalized medicine by means of genotyping for inter-individual variability in drug action and metabolism. Gene-environment interactions may explain why some subjects become depressed while others remain unaffected. The aim of this book is to describe current knowledge of MDD from the point of view of neurobiology, molecular genetics and cognition. The authors address a deep understanding of cognitive and neurobiological mechanisms involved in MDD.
BT  - Major Depressive Disorder
SP  - Ch. 5
UR  - https://doi.org/10.5772/59374
DO  - 10.5772/59374
SN  - 
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-23
ER  -