TY - CHAP AU - Lee Roy Morgan AU - Andrew H. Rodgers AU - Gerard Bastian AU - Edmund Benes AU - William S. Waud AU - Christopher Papagiannis AU - Dan Krietlow AU - Branko S. Jursic AU - Robert F. Struck AU - Gerald LaHoste AU - Melissa Thornton AU - Melody Luttrell AU - Edward Stevens AU - Rodger Thompson ED - Lee Roy Morgan Y1 - 2014-06-11 PY - 2014 T1 - Comparative Preclinical Pharmacology and Toxicology for 4- demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOCPEN) — A Potential Neuro-Alkylating Agent for Glioblastoma (GBM) and Metastatic Cancers Involving the Central Nervous System N2 - A novel concept that is reviewed and discussed in several chapters in the book alludes to the transport of drugs bound to red blood cells into the highly vascular CNS tumors - both primary and metastatic. Such a transport mechanism is unique and of significant therapeutic potential. It is hopeful that the novel information presented in this book will result in new approaches to the treatment CNS tumors. BT - Tumors of the Central Nervous System SP - Ch. 9 UR - https://doi.org/10.5772/58353 DO - 10.5772/58353 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-23 ER -