TY - CHAP AU - Rubén Marín-Juez AU - Encarnación Capilla AU - Francisco Carvalho-Simoes AU - Marta Camps AU - Josep V. Planas ED - Leszek Szablewski Y1 - 2014-06-18 PY - 2014 T1 - Structural and Functional Evolution of Glucose Transporter 4 (GLUT4): A Look at GLUT4 in Fish N2 - Most tissues and organs, such as the brain, need glucose constantly, as an important source of energy. The low blood concentrations of glucose (hypoglycemia) can cause seizures, loss of consciousness, and death. On the other hand, long lasting elevation of blood glucose concentrations (hyperglycemia) can result in blindness, renal failure, cardiac and peripheral vascular disease, and neuropathy. Therefore, blood glucose concentrations need to be maintained within narrow limits. The process of maintaining blood glucose at a steady-state level is called glucose homeostasis. This is accomplished by the finely hormone regulation of peripheral glucose uptake (glucose utilization), hepatic glucose production and glucose uptake during carbohydrates ingestion. BT - Glucose Homeostasis SP - Ch. 2 UR - https://doi.org/10.5772/58094 DO - 10.5772/58094 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-24 ER -