TY - CHAP AU - Maria Clara Bicho AU - Alda Pereira da Silva AU - Rui Medeiros AU - Manuel Bicho ED - Sabina Janciauskiene Y1 - 2013-07-24 PY - 2013 T1 - The Role of Haptoglobin and Its Genetic Polymorphism in Cancer: A Review N2 - The magnitude and rapidity of the changes in the concentrations of APPs, together with their short half-life, suggest an important role for these proteins in the establishment of host defense. APPs are regarded as having general functions in trapping of micro-organisms and their products, in activating complement, in binding cellular remnants like nuclear fractions, in neutralizing enzymes, scavenging free radicals, and in modulating the hosts immune response. Despite vast pro- and anti-inflammatory properties ascribed to individual APPs, their function during health and disease remains incompletely defined. BT - Acute Phase Proteins SP - Ch. 3 UR - https://doi.org/10.5772/56695 DO - 10.5772/56695 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-03-28 ER -