TY - CHAP AU - Mikael Larsson AU - Tsai-Mu Cheng AU - Cheng-Yu Chen AU - Simon J. T. Mao ED - Sabina Janciauskiene Y1 - 2013-07-24 PY - 2013 T1 - Unique Assembly Structure of Human Haptoglobin Phenotypes 1-1, 2-1, and 2-2 and a Predominant Hp 1 Allele Hypothesis N2 - The magnitude and rapidity of the changes in the concentrations of APPs, together with their short half-life, suggest an important role for these proteins in the establishment of host defense. APPs are regarded as having general functions in trapping of micro-organisms and their products, in activating complement, in binding cellular remnants like nuclear fractions, in neutralizing enzymes, scavenging free radicals, and in modulating the hosts immune response. Despite vast pro- and anti-inflammatory properties ascribed to individual APPs, their function during health and disease remains incompletely defined. BT - Acute Phase Proteins SP - Ch. 7 UR - https://doi.org/10.5772/56048 DO - 10.5772/56048 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-24 ER -