TY - CHAP AU - Faraz Tariq Farooq AU - Martin Holcik AU - Alex MacKenzie ED - Uday Kishore Y1 - 2013-05-15 PY - 2013 T1 - Spinal Muscular Atrophy: Classification, Diagnosis, Background, Molecular Mechanism and Development of Therapeutics N2 - This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking. BT - Neurodegenerative Diseases SP - Ch. 23 UR - https://doi.org/10.5772/53800 DO - 10.5772/53800 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-26 ER -