TY - CHAP AU - Thabata Lopes Alberto Duque AU - Xênia Macedo Souto AU - Valter Viana de Andrade-Neto AU - Vítor Ennes-Vidal AU - Rubem Figueiredo Sadok Menna-Barreto ED - Yannick Bailly Y1 - 2013-04-17 PY - 2013 T1 - Autophagic Balance Between Mammals and Protozoa: A Molecular, Biochemical and Morphological Review of Apicomplexa and Trypanosomatidae Infections N2 - The chapters in this book review the latest advances in the molecular mechanisms of autophagy, highlighting some of the most challenging research topics. The focus is mainly on how this basic cell defense mechanism comes into play in various pathologies, including liver diseases, myopathies, infectious diseases, cancers and neurodegenerative diseases. In these diseases, the contradictory autophagy roles of cell survival versus cell death emphasize the necessity of taking into account this double-edged nature in future development of already promising, autophagy- modulating, therapies. BT - Autophagy - A Double-Edged Sword SP - Ch. 14 UR - https://doi.org/10.5772/54970 DO - 10.5772/54970 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-25 ER -