TY - CHAP AU - Masafumi Kuramoto AU - Shinya Shimada AU - Satoshi Ikeshima AU - Kenichiro Yamamoto AU - Toshiro Masuda AU - Tatsunori Miyata AU - Shinichi Yoshimatsu AU - Masayuki Urata AU - Hideo Baba ED - Daniela Laz?r Y1 - 2013-01-23 PY - 2013 T1 - Fetal-type Glycogen Phosphorylase (FGP)Expression in Intestinal Metaplasia as a High Risk Factor of the Development of Gastric Carcinoma N2 - Gastric cancer is the second most common cause of cancer-related death in the world. There are no screening tests available for its diagnosis, therefore patients usually presents in late stages, associated with poor prognosis. Currently, many efforts are made toward new advances in the treatment strategies. The book makes an insight into the assessment of premalignant lesions, current management of early gastric cancer, risk and protective factors in gastric carcinogenesis. "Gastric cancer" provides a detailed description of the morphologic classification, molecular changes and epigenetic alterations of this tumor. The book describes the role of different diagnostic tools in the preoperative assessment of patients and the most important factors contributing to the prognosis. Moreover, it describes the current surgical and chemotherapeutic options for gastric neoplasm. This publication may open new and interesting gates for further research concerning carcinogenesis, genetic and epigenetic alterations, signaling pathways, H. pylori infection, the discovery of protective factors against gastric cancer and of revolutionary therapies of this tumor. BT - Gastric Carcinoma SP - Ch. 5 UR - https://doi.org/10.5772/51793 DO - 10.5772/51793 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-26 ER -