TY  - CHAP
AU  - Martin Gutierrez Martin
AU  - Maria Soledad Romero Colas
AU  - 
AU  - Jose Antonio Moreno Chulilla
ED  - Sarika Arora
Y1  - 2012-06-29
PY  - 2012
T1  - Iron Deficiency in Hemodialysis Patients – Evaluation of a Combined Treatment with Iron Sucrose and Erythropoietin-Alpha: Predictors of Response, Efficacy and Safety
N2  - Iron has various functions in the body, including the metabolism of oxygen in a variety of biochemical processes. Iron, as either heme or in its "nonheme" form, plays an important role in key reactions of DNA synthesis and energy production.  
However, low solubility of iron in body fluids and the ability to form toxic hydroxyl radicals in presence of oxygen make iron uptake, use and storage a serious challenge. The discovery of new metal transporters, receptors and peptides and as well as the discovery of new cross-interactions between known proteins are now leading to a breakthrough in the understanding of systemic iron metabolism. The objective of this book is to review and summarize recent developments in our understanding of iron transport and storage in living systems.
BT  - Iron Metabolism
SP  - Ch. 4
UR  - https://doi.org/10.5772/34481
DO  - 10.5772/34481
SN  - 
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-19
ER  -