TY  - CHAP
AU  - Vaclav Liska
AU  - Vladislav Treska
AU  - Hynek Mirka
AU  - Ondrej Vycital
AU  - Jan Bruha
AU  - Pavel Pitule
AU  - Jana Kopalova
AU  - Tomas Skalicky
AU  - Alan Sutnar
AU  - Jan Benes
AU  - Jiri Kobr
AU  - Alena Chlumska
AU  - Jaroslav Racek
AU  - Ladislav Trefil
ED  - Pedro M. Baptista
Y1  - 2012-05-16
PY  - 2012
T1  - Liver Parenchyma Regeneration in Connection with Extended Surgical Procedure - Experiment on Large Animal
N2  - Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in restoring the liver to its normal function after injury have been resolutely described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization.
This book describes some of the complex mechanisms involved in liver regeneration and provides examples of the most up-to-date strategies used to induce liver regeneration, both in the clinic and in the laboratory. The information presented will hopefully benefit not only professionals in the liver field, but also people in other areas of science (pharmacology, toxicology, etc) that wish to expand their knowledge of the fundamental biology that orchestrates liver injury and regeneration.
BT  - Liver Regeneration
SP  - Ch. 9
UR  - https://doi.org/10.5772/38130
DO  - 10.5772/38130
SN  - 
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-27
ER  -