TY  - CHAP
AU  - Jayson Yap
AU  - Mohammad G. Saklayen
ED  - John S. D. Chan
Y1  - 2012-04-20
PY  - 2012
T1  - Diabetic Nephropathy: Role of Aldosterone and Benefits of Therapy with Aldosterone Receptor Blocker
N2  - Internationally renowned experts have provided data on their own studies, and discuss the relative usefulness of their work in relation to diabetic nephropathy. The first section describes the novel role of intrarenal renin-angiotensin-aldosterone system (RAAS) and oxidative stress in the development of diabetic nephropathy and discusses the current and novel pharmacological interventions in the treatment of diabetic nephropathy. The second section discusses other important contributors outside of the RAAS in the pathogenesis of diabetic nephropathy including AGE/RAGE, epithelial-mesenchymal-transition (EMT) and immune cytokines. 
Features:
Provides novel information on various pathophysiological determinants in the development of diabetic nephropathy
Provides novel information on various pharmacological interventions of diabetic nephropathy
BT  - Diabetic Nephropathy
SP  - Ch. 3
UR  - https://doi.org/10.5772/34854
DO  - 10.5772/34854
SN  - 
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-25
ER  -