TY - CHAP AU - Çetin Aggar AU - Philip G. De Groot AU - Joost C.M. Meijers ED - Alena Bulikova Y1 - 2012-04-20 PY - 2012 T1 - Structural Changes in β2-Glycoprotein I and the Antiphospholipid Syndrome N2 - The antiphospholipid syndrome has been described for the first time by Graham Hughes in 1983 as a condition connected with thromboses or foetal losses and antiphospholipid antibodies presence. Form that time there has been a great progress in knowledge, including antiphospholipid antibodies characterisation, their probable and also possible action, clinical manifestations, laboratory detection and treatment possibilities . This book provides a wide spectrum of clinical manifestations through Chapters written by well known researchers and clinicians with a great practical experience in management of diagnostics or treatment of antiphospholipid antibodies' presence. BT - Antiphospholipid Syndrome SP - Ch. 2 UR - https://doi.org/10.5772/30834 DO - 10.5772/30834 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-05-10 ER -