TY - CHAP AU - Natacha Entz-Werlé ED - Manish Agarwal Y1 - 2012-04-11 PY - 2012 T1 - Bone Formation Deregulations Are the Oncogenesis Keys in Osteosarcomas N2 - This book is aimed at quickly updating the reader on osteosarcoma, a dreaded primary bone cancer. Progress in management of osteosarcoma has been slow after the evolution of chemotherapy and limb salvage surgery. Research is now directed towards identifying molecular targets for systemic therapy. Availability of chemotherapy drugs and low cost implants in developing world have allowed limb salvage surgery to develop. This book looks at current basic knowledge on osteosarcoma and some of the developments in research which have the potential to change the prognosis. BT - Osteosarcoma SP - Ch. 6 UR - https://doi.org/10.5772/30693 DO - 10.5772/30693 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-19 ER -