TY - CHAP AU - Nur Mohammad Monsur Hassan AU - Mitsuhiro Tada AU - Jun-ichi Hamada AU - Masanobu Shindoh AU - Haruhiko Kashiwazaki AU - Yutaka Yamazaki AU - Yuichi Ashikaga AU - Tetsuya Moriuchi AU - Nobuo Inoue AU - Akira Sasaki ED - Kalu U. E. Ogbureke Y1 - 2012-03-14 PY - 2012 T1 - p53 Mutation and Multiple Primary Oral Squamous Cell Carcinomas N2 - Oral cancer is a significant public health challenge globally. Although the oral cavity is easily accessible, early diagnosis remains slow compared to the enhanced detection of cancers of the breast, colon, prostate, and melanoma. As a result, the mortality rate from oral cancer for the past four decades has remained high at over 50% in spite of advances in treatment modalities. This contrasts with considerable decrease in mortality rates for cancers of the breast, colon, prostate, and melanoma during the same period. This book attempts to provide a reference-friendly update on the etiologic/risk factors, current clinical diagnostic tools, management philosophies, molecular biomarkers, and progression indicators of oral cancer. BT - Oral Cancer SP - Ch. 8 UR - https://doi.org/10.5772/35453 DO - 10.5772/35453 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-25 ER -