TY - CHAP AU - Wataru Yoshida AU - Akihisa Kamataki AU - Miwa Uzuki AU - Takashi Sawai ED - Qian Chen Y1 - 2012-03-02 PY - 2012 T1 - Evaluation of In Vivo Proteolytic Activity N2 - Osteoarthritis is one of the most debilitating diseases affecting millions of people worldwide. However, there is no FDA approved disease modifying drug specifically for OA. Surgery remains an effective last resort to restore the function of the joints. As the aging populations increase worldwide, the number of OA patients increases dramatically in recent years and is expected to increase in many years to come. This is a book that summarizes recent advance in OA diagnosis, treatment, and surgery. It includes wide ranging topics from the cutting edge gene therapy to alternative medicine. Such multifaceted approaches are necessary to develop novel and effective therapy to cure OA in the future. In this book, different surgical methods are described to restore the function of the joints. In addition, various treatment options are presented, mainly to reduce the pain and enhance the life quality of the OA patients. BT - Osteoarthritis SP - Ch. 15 UR - https://doi.org/10.5772/25951 DO - 10.5772/25951 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-20 ER -