TY - CHAP AU - Tatyana Azhikina AU - Timofey Skvortsov ED - Pere-Joan Cardona Y1 - 2012-02-17 PY - 2012 T1 - Mycobacterium tuberculosis Transcriptome In Vivo Studies – A Key to Understand the Pathogen Adaptation Mechanism N2 - Mycobacterium tuberculosis, as recent investigations demonstrate, has a complex signaling expression, which allows its close interaction with the environment and one of its most renowned properties: the ability to persist for long periods of time under a non-replicative status. Although this skill is well characterized in other bacteria, the intrinsically very slow growth rate of Mycobium tuberculosis, together with a very thick and complex cell wall, makes this pathogen specially adapted to the stress that could be generated by the host against them. In this book, different aspects of these properties are displayed by specialists in the field. BT - Understanding Tuberculosis SP - Ch. 7 UR - https://doi.org/10.5772/31052 DO - 10.5772/31052 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-05-11 ER -