TY - CHAP AU - Jeanette Henningsen AU - Blagoy Blagoev AU - Irina Kratchmarova ED - Tsz-Kwong Man ED - Ricardo J. Flores Y1 - 2012-02-10 PY - 2012 T1 - Quantitative Proteomics for Investigation of Secreted Factors: Focus on Muscle Secretome N2 - Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research. BT - Proteomics SP - Ch. 19 UR - https://doi.org/10.5772/30820 DO - 10.5772/30820 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-03-28 ER -