TY - CHAP AU - Toshinari Minamoto AU - Masanori Kotake Mitsutoshi Nakada AU - Takeo Shimasaki AU - Yoshiharu Motoo AU - Kazuyuki Kawakami ED - Rajunor Ettarh Y1 - 2012-02-10 PY - 2012 T1 - Distinct Pathologic Roles for Glycogen Synthase Kinase 3β in Colorectal Cancer Progression N2 - Colorectal cancer is a common disease, affecting millions worldwide and represents a global health problem. Effective therapeutic solutions and control measures for the disease will come from the collective research efforts of clinicians and scientists worldwide. This book presents the current status of the strides being made to understand the fundamental scientific basis of colorectal cancer. It provides contributions from scientists, clinicians and investigators from 20 different countries. The four sections of this volume examine the evidence and data in relation to genes and various polymorphisms, tumor microenvironment and infections associated with colorectal cancer. An increasingly better appreciation of the complex inter-connected basic biology of colorectal cancer will translate into effective measures for management and treatment of the disease. Research scientists and investigators as well as clinicians searching for a good understanding of the disease will find this book useful. BT - Colorectal Cancer Biology SP - Ch. 6 UR - https://doi.org/10.5772/28036 DO - 10.5772/28036 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-24 ER -