TY  - CHAP
AU  - Hao-Chih Tai
AU  - Ching-Fu Tu
AU  - Tien-Shuh Yang
AU  - Jang-Ming Lee
AU  - San-Yuan Huang
AU  - 
AU  - Bao-Tyan Wang
ED  - Shuji Miyagawa
Y1  - 2012-02-03
PY  - 2012
T1  - Function Measurements of HLA-II Transgenic Pigs for Xenotransplantation
N2  - Accompanied by the advent of animal cloning, the technique of nuclear transfer produced alpha1,3-galactosyltransferase-knockout (Gal-KO) pigs in many institutes, including the ones in Japan, at the beginning of 21st Century. In addition, the controversy of the risks of PERV has gradually minimized, because of the fact that there are no cases of PERV infections reported in humans. Furthermore, a large clinical wave for islet allotransplantation resumed the interest of xenotransplantation, especially porcine islet transplantation and some exceptions. Clinical trials were done in many countries so far, such as Sweden, China, Mexico, USA  (Inventory of Human Xenotransplantation Practices - IXA and HUG in collaboration with WHO). In addition, a new clinical trial was approved by the government, and resumed the porcine islet transplantation research in New Zealand two years ago.
BT  - Xenotransplantation
SP  - Ch. 4
UR  - https://doi.org/10.5772/34018
DO  - 10.5772/34018
SN  - 
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-05-07
ER  -