TY - CHAP AU - Pieter Hindryckx AU - Debby Laukens ED - Sami Karoui Y1 - 2012-01-27 PY - 2012 T1 - Intestinal Barrier Dysfunction: The Primary Driver of IBD? N2 - This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such as intestinal barrier dysfunction and the roles of TH 17 cells and IL 17 in the immune response in inflammatory bowel disease. The book also focuses on several relevant clinical points, such as pregnancy during inflammatory bowel disease and the health-related quality of life as an end point of the different treatments of the diseases. Finally, advances in management of patients with inflammatory bowel disease are discussed, especially in a complete review of the recent literature. BT - Inflammatory Bowel Disease SP - Ch. 2 UR - https://doi.org/10.5772/26436 DO - 10.5772/26436 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-27 ER -