TY - CHAP AU - Jakyung Yoo AU - JoseĢ L. Medina-Franco ED - Chris Rundfeldt Y1 - 2011-12-07 PY - 2011 T1 - Discovery and Optimization of Inhibitors of DNA Methyltransferase as Novel Drugs for Cancer Therapy N2 - This book represents a case study based overview of many different aspects of drug development, ranging from target identification and characterization to chemical optimization for efficacy and safety, as well as bioproduction of natural products utilizing for example lichen. In the last section, special aspects of the formal drug development process are discussed. Since drug development is a highly complex multidisciplinary process, case studies are an excellent tool to obtain insight in this field. While each chapter gives specific insight and may be read as an independent source of information, the whole book represents a unique collection of different facets giving insight in the complexity of drug development. BT - Drug Development SP - Ch. 1 UR - https://doi.org/10.5772/27742 DO - 10.5772/27742 SN - PB - IntechOpen CY - Rijeka Y2 - 2024-04-19 ER -