TY  - CHAP
AU  - Gunthard Stübs
AU  - Ralf R. Schumann
ED  - Neuza S. Sato
Y1  - 2011-11-21
PY  - 2011
T1  - Recognition of Treponema pallidum and Other Spirochetes by the Innate Immune System
N2  - Syphilis, a sexually transmitted disease was first described in 15th century, is caused by Treponema pallidum subsp. pallidum and occurs worldwide. This book is a collection of chapters presenting the novel knowledge about the T. pallidum and some historical and up to date information about venereal disease and syphilis. The collection of articles includes: immunological aspects recognition of T. pallidum by the pattern recognition receptors of the innate immune; the whole genome analysis of treponemes and new targets for its molecular diagnosis; some historical aspects of venereal diseases treatment;  natural history of syphilis including clinical manifestation and epidemiology; a clinical aspects dealing with psychiatric manifestations of neurosyphilis; spatial and temporal patterns of primary syphilis and secondary syphilis described by the spatial and space-time scan statistics; a commonly used methods for laboratorial diagnosis, the serological response to treatment of syphilis and safety in blood transfusion. I hope this book will be useful for students and research fellows as well for the wide audience.
BT  - Syphilis
SP  - Ch. 1
UR  - https://doi.org/10.5772/25127
DO  - 10.5772/25127
SN  - 
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-23
ER  -