Open access peer-reviewed Monograph

Update on Hepatitis C

Edited by Martina Smolic

University of Osijek, Croatia


In the past few years, remarkable progress has been made in our understanding of HCV biology, pathogenesis of infection, and structure-function relationships. This has led to quantum advances in clinical efficacy and tolerability. Yet, in spite of this amazing progress, there remain obstacles to widespread successful treatment. These issues include biological failures even with direct-acting agents, lack of options for individual with organ failures, drug-drug interactions, access to medications either due to lack of availability or affordability, and psychiatric and social issues. These problems are likely to remain in the future. Therefore, this book has been created by distinguished faculties from around the world to address the progress in our understanding of HCV infection and to review new treatment options, limitations, and accessibility of new therapeutic options.

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Update on Hepatitis CEdited by Martina Smolic

Published: October 4th 2017

DOI: 10.5772/66769

ISBN: 978-953-51-3564-7

Print ISBN: 978-953-51-3563-0

eBook (PDF) ISBN: 978-953-51-4630-8

Copyright year: 2017

Books open for chapter submissions

15557 Total Chapter Downloads

4 Crossref Citations

1 Web of Science Citations

13 Dimensions Citations


Open access peer-reviewed

1. A Brief Update on the Treatment of Hepatitis C

By Alyssa M. Austria, Vjera Ninčević and George Y. Wu


Open access peer-reviewed

2. Hepatitis C Virus (HCV) Treatment in Croatia: Recent Advances and Ongoing Obstacles

By Marko Duvnjak, Nina Blažević and Lucija Virović Jukić


Open access peer-reviewed

3. Liver Transplantation in Patients with Hepatitis C

By Tajana Filipec Kanižaj


Open access peer-reviewed

4. Impact of HBV Infection on Outcomes of Direct-Acting Antiviral Therapy of Chronic Hepatitis C

By Kazuhiko Hayashi, Masatoshi Ishigami, Yoji Ishizu, Teiji Kuzuya, Takashi Honda, Yoshihiko Tachi, Tetsuya Ishikawa, Yoshiaki Katano, Kentaro Yoshioka, Hidenori Toyoda, Takashi Kumada, Hidemi Goto and Yoshiki Hirooka


Open access peer-reviewed

5. Current Therapeutic Options for HCV-HIV Coinfection

By Ljiljana Perić and Dario Sabadi


Open access peer-reviewed

6. Hepatitis C Treatment in Elderly Patients

By Takashi Honda, Masatoshi Ishigami, Kazuhiko Hayashi, Teiji Kuzuya, Yoji Ishizu, Yoshiki Hirooka and Hidemi Goto


Open access peer-reviewed

7. Direct-Acting Antivirals (DAAs): Drug-Drug Interactions (DDIs) in the Treatment of Hepatitis C Virus (HCV)

By Sabina Steiner, Nikola Raguž-Lučić and Damir Erceg


Open access peer-reviewed

8. Resistance to Direct-Acting Antiviral Agents in Treatment of Hepatitis C Virus Infections

By Mostafa K. El Awady and Reham M. Dawood


Open access peer-reviewed

9. Extrahepatic Manifestations of Hepatitis C Virus Infection

By Lucija Virović Jukić and Dominik Kralj


Open access peer-reviewed

10. Hepatitis C–Associated Diabetes Mellitus

By Ines Bilić-Ćurčić, Hrvoje Roguljić, Marul Ivandić, Aleksandar Včev, Robert Smolić and Martina Smolić


Open access peer-reviewed

11. Neuropathological and Neuropsychiatric Determinants in HCV- Infected Patients

By Vanja Vojnović


Open access peer-reviewed

12. HCV and Work Ability Assessment

By Milan Milošević, Jelena Jakab, Lucija Kuna and Martina Smolić


Open access peer-reviewed

13. Health-Related Quality of Life in Antiviral-Treated Chronic Hepatitis C Patients

By Aleksandar Včev, Jelena Jakab, Lucija Kuna and Martina Smolić


Open access peer-reviewed

14. Pharmacogenomic Testing in the Era of Patient-Tailored HCV Treatment

By Martina Smolić, Tea Omanović, Ivana Božić, Ines Bilić-Ćurčić, Robert Smolić and Aleksandar Včev


Open access peer-reviewed

15. Progress in Vaccine Development for HCV Infection

By Ashraf Tabll, Reem El-Shenawy and Yasmine El Abd


Open access peer-reviewed

16. Approaches and Considerations for the Successful Treatment of HCV Infection

By Robert Smolić, Jelena Jakab, Lucija Kuna, Martina Smolić, Martina Kajić, Marinko Žulj and Aleksandar Včev


Open access peer-reviewed

17. The Molecular Basis of Anti-HCV Drug Resistance

By Shaina M. Lynch and George Y. Wu


Monograph and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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