Open access peer-reviewed Edited Volume

Update on Amyotrophic Lateral Sclerosis

Edited by Humberto Foyaca Sibat

Walter Sisulu University


Lourdes de Fátima Ibañez-Valdés

Walter Susulu University

This book contains selected peer-reviewed chapters which cover updated information on ALS written by international researchers. Update on Amyotrophic Lateral Sclerosis is comprised of 13 chapters from some of the world's top central nervous system researchers and neurologists to provide a timely review of the most recent developments in ALS, covering historic aspects, experimental animal models, genetics, pathogenesis, clinical aspects and imagenology among others. Contributors from Belgium, France, Japan, India, Italy, Mexico, Russia, South Africa, and Switzerland have collaborated enthusiastically and efficiently, dedicating their time to create this reader-friendly yet comprehensive work which includes many explanatory figures, tables and photos to enhance legibility and make the book clinically useful. We are looking forward with confidence and pride in the remarkable role that this book will play for a new vision and mission.

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Update on Amyotrophic Lateral SclerosisEdited by Humberto Foyaca Sibat

Published: September 14th 2016

DOI: 10.5772/61682

ISBN: 978-953-51-2601-0

Print ISBN: 978-953-51-2600-3

eBook (PDF) ISBN: 978-953-51-4183-9

Copyright year: 2016

Books open for chapter submissions

17187 Total Chapter Downloads

6 Crossref Citations

1 Web of Science Citations

7 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Introduction to Update in Amyotrophic Lateral Sclerosis and Review of this Condition in Sportsmen

By Humberto Foyaca-Sibat and Lourdes de Fátima Ibañez-Valdés


Open access peer-reviewed

2. PET Imaging in ALS

By Bart Swinnen, Koen Van Laere and Philip Van Damme


Open access peer-reviewed

3. Motor Cortex Hyperexcitability, Neuroplasticity, and Degeneration in Amyotrophic Lateral Sclerosis

By Ilya S. Bakulin, Alexander V. Chervyakov, Natalia A. Suponeva, Maria N. Zakharova and Michael A. Piradov


Open access peer-reviewed

4. SOD1, from Bench to Bed: New Role for the Oldest Protein Implicated in ALS

By Diamanti Luca, Zucchi Elisabetta, Pansarasa Orietta, Ceroni Mauro and Cereda Crisitna


Open access peer-reviewed

5. Role of Cysteine Residue of Mutant Cu, Zn‐Superoxide Dismutase (SOD1) in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS)

By Seiichi Nagano and Toshiyuki Araki


Open access peer-reviewed

6. Influence of Repeats in the Protein Chain on its Aggregation Capacity for ALS-Associated Proteins

By Oxana V. Galzitskaya


Open access peer-reviewed

7. MicroRNAs in Amyotrophic Lateral Sclerosis

By Maria Teresa Gonzalez Garza


Open access peer-reviewed

8. Tiny microRNAs Fine-Tune Amyotrophic Lateral Sclerosis Regulation

By Utpal Bhadra, Anisha Pal, Jagamohan Chhatai and Manika Pal Bhadra


Open access peer-reviewed

9. Selective Vulnerability of Neuronal Subtypes in ALS: A Fertile Ground for the Identification of Therapeutic Targets

By Cylia Rochat, Nathalie Bernard-Marissal and Bernard L. Schneider


Open access peer-reviewed

10. Neuronal Intermediate Filaments in Amyotrophic Lateral Sclerosis

By Philippe Codron, Julien Cassereau, Joël Eyer and Franck Letournel


Open access peer-reviewed

11. Trophic Factors in the Therapeutic Challenge Against ALS: Current Research Directions

By Anna Sobuś and Bogusław Machaliński


Open access peer-reviewed

12. Molecular Taxonomy: Use of Transcriptional Profiles to Identify Different ALS Subtypes

By Giovanna Morello, Francesca Luisa Conforti, Antonio Gianmaria Spampinato and Sebastiano Cavallaro


Open access peer-reviewed

13. Amyotrophic Lateral Sclerosis: Role of the Canonical Wnt/Beta- Catenin Pathway and PPAR Gamma

By Yves Lecarpentier and Alexandre Vallée


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI
  • BKCI
  • BIOSIS Previews

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